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MEDLINE Searching Using OvidWeb

Searching Ovid MEDLINEŽ

What is MEDLINE?
MEDLINE: NOT just another Internet search engine
Getting connected to Ovid MEDLINEŽ
Basic MEDLINE searching
Tricks for refining your search
Combining sets
AND versus OR
Limiting a search
Viewing and selecting results
Printing, emailing, and saving results
Getting the full-text of the article
Author, title, or journal searches
Find similar articles and citing articles
Clinical Queries
Troubleshooting your results
For more help

What is MEDLINE?

MEDLINE is the United States' National Library of Medicine's premier bibliographic index to the biomedical journal literature.  It covers:

  • all health sciences including medicine, nursing, dentistry, allied health, and veterinary medicine
  • the pre-clinical sciences such as biology, biochemistry, genetics, microbiology, physiology, and anatomy
  • related disciplines such as health care administration, biomedical engineering, clinical nutrition, psychology, and social work.

MEDLINE provides citations and abstracts to journal articles and other professional publications.  It provides coverage from the 1950s to the present, contains over 16 million records, and indexes approximately 4800 journals published in the United States and over 70 other countries.  MEDLINE is available at Dana Medical Library through Ovid Technologies, a commercial vendor.

MEDLINE: Not just another Internet search engine

MEDLINE, as an electronic database, was created long before the advent of powerful Internet search engines capable of performing rapid keyword searches.  Although keyword searches can be done in MEDLINE, the main search mechanism is through the use of subject headings (often referred to simply as "terms").  These can be likened to the terms found in the back-of-the-book index of a typical textbook that aid the reader in rapidly locating the page on which a given topic is discussed.  Similarly, the MEDLINE subject headings are used to quickly find any records in the database on that topic.

Each article indexed in MEDLINE is assigned an average of 10-12 subject headings, based on its subject content.  The subject headings are assigned by human indexers through manual review of the article, not by computer algorithm.  For any search term entered, the Ovid software will automatically display a list of possible MEDLINE subject headings from which to make selections.

Although there is the option to search by keyword in MEDLINE, searching via the subject headings will usually produce better results with fewer irrelevant hits.  Exceptions to this rule do exist, for example when searching for proper names, trade names, specialized jargon, and newly coined terms. 

Connecting to Ovid MEDLINEŽ

From Dana Library's home page (http://library.uvm.edu/dana), click on "OVID" under "Databases & E-Books". Select the desired segment of Ovid MEDLINEŽ, or choose the entire database, including "In-Process Citations and other Non-Indexed Citations". 

For off-campus access to Ovid MEDLINEŽ, click on the "Connect From Off Campus" button on the left sidebar of Dana Library's home page for instructions and links.

Basic MEDLINE searching

One of the most crucial steps to performing a successful literature search is formulating a search question and then identifying the searchable concepts.  

Let's suppose you want to find articles discussing the use of Factor VII in the treatment of intracerebral hemorrhage.  Here the most likely searchable concepts are "Factor VII" and "intracerebral hemorrhage", although other terms may produce relevant results as well. 

Once you have identified the searchable concepts, search on each one separately rather than as a multiple word string.  When you have created a separate set for each concept, combine the sets. 

Using the above example, begin by connecting to Ovid MEDLINEŽ.  Then...

  • For the first concept, enter "Factor VII"  in the search box, and click Search or simply press the Enter key. 
  • In the mapping display, check the box next to the one most appropriate term from the list displayed.  In this case there is only one subject heading displayed, but often there are many more.   As explained above, select the keyword option only as a last resort.  For this example, check the box next to "Factor VII". 
  • Optional step:  to view a short definition (Scope Note) for a particular term, click on  the small blue information icon ("i").   This will identify synonyms, related terms, and the year the term was introduced into the vocabulary list. 
  • Any term selected will automatically be exploded unless you un-check the Auto-Explode box.  (See the Explode section under "Tricks for refining your search".) 
  • Check the Focus box if desired.  (See the Focus section under "Tricks for refining your search".)  
  • Click Continue. 
  • Select one or more subheadings, or accept the default option to Include All Subheadings. 
  • Click Continue.  You will now be back at the Main Search Page, having generated the first set of your literature search.   
  • Now enter the second term, "intracerebral hemorrhage", and repeat the above steps to generate a second set of results.  Click on the scope note to verify that "Cerebral hemorrhage" is the appropriate subject heading. 
  • Read the next section for tips on refining your search, or skip to Combining Sets. 

Tricks for refining your search

MEDLINE provides a number of powerful tools with which to fine tune your search and eliminate less relevant hits.  These can be used alone or in any combination.

Explode

When you explode a term, you direct the system to search for that term, plus any more specific terms associated with it.   For example, if you explode the term "Wounds and Injuries", your search will include all the specific types of wounds such as burns, contusions, fractures, etc., as well as the more general term.   Alternatively, you may choose not to explode, prompting the system to search only on the general term but not the more specific terms.  

In order to decide if you want to explode, click on the hyperlinked term in the mapping display to access the hierarchical list of subject headings.  Scroll down until you encounter the highlighted original term.  Note that with each successive indentation, the terms become progressively more specific.  To explode, check the box in the explode column next to the broader term. 

If you explode a term, the result will be a larger set than if you searched only on the more general term.  Use this feature with caution, as you may or may not want to search on all the more specific terms.  

Continuing with the above example, you'll note that the term "Cerebral Hemorrhage" has two more specific terms nested beneath it, "Basal Ganglia Hemorrhage" and "Traumatic Cerebral Hemorrhage".  In this case, exploding will probably be helpful.  Similarly, the term "Factor VII" has a narrower term, "Factor VIIa (activated)", which you'll probably also want to include in your search strategy. 

By default, Ovid MEDLINEŽ will explode any subject heading you select unless you direct the system otherwise.  In the search history display, the code "exp" will precede any subject heading that was exploded.

Focus

The focus feature will limit your search to articles in which the term is the main topic, eliminating those with only a very brief or general discussion of the term.  The final result will be a smaller, more "focused" set of citations, since the less relevant citations will have been excluded.  Using the focus feature is one of the most effective methods for reducing the total number of hits while simultaneously maintaining or increasing overall relevancy. The term "Cerebral Hemorrhage" produces a very large number of hits, so it may be helpful to use the focus feature in this example.

In the search history display, an asterisk will precede any subject heading that was "focused". 

Subheadings

Subheadings allow you to concentrate your search on one particular aspect of a subject.  In our example, since you are primarily interested in the therapeutic treatment of intracerebral hemorrhage, you could select the "Drug Therapy" subheading. 

Like the focus feature, the use of subheadings has the effect of producing a smaller total number of hits, while increasing the overall relevancy of the set.  However, you run the risk of accidentally eliminating some relevant citations by using subheadings, so use this feature with caution. 

Combining sets

After creating a separate set of results for each concept, combine the sets by clicking on the Combine Searches button.  Select the sets you wish to combine, and click Continue.

You'll need to decide if you want to combine the sets using AND or OR.  The default is AND.  It's use will result in a smaller set of results, in which each citation will be listed under both subject headings.  Refer to the following section for a detailed explanation of AND and OR.

AND versus OR

To understand the difference between the Boolean operators AND and OR, it may help to think of them in terms of making a purchase.   Suppose you need to buy a new car, and need to make decisions regarding body type, engine size, and color, among other characteristics.   

Let's say you decide that you want a silver 4-door sedan with a 6-cylinder engine.  Expressed in Boolean terms, you would say you want a "4-door sedan AND 6-cylinder engine AND silver".  The Boolean operator AND will generate a relatively small set of cars of which each will satisfy all the criteria.   It will NOT include any cars that are missing any one of the criteria, even if they have the other two.  Thus, it will not include any cars that are not silver in color, even if they are 4-door sedans and/or have a 6-cylinder engine. 

Conversely, suppose you are very flexible in your desires and you decide that you would indeed be perfectly happy with a car that is either a 4-door sedan OR a 6-cylinder engine OR is silver in color.  Here, the Boolean operator OR will create a relatively large set of cars, each of which will satisfy at least one of the criteria but not necessarily all of them.  So you may have many 4-door sedans to choose from, but they may or may not have a 6-cylinder engine and they may or may not be silver in color.

Many techniques used in database searching are based on the principles of Boolean logic (or Boolean algebra).  For the curious among us, the term "Boolean" comes from George Boole, the 19th century English mathematician who developed this system of logic.  If you'd like to learn more, check out this web page from Creighton University.   http://www.hsl.creighton.edu/hsl/Searching/Boolean_operations.html

Limiting

Develop your search strategy before applying limits.

The most commonly used limits, including Humans, English Language, Core Clinical Journals, and Local Holdings, are provided just below the search box on the Main Search Page.  The Local Holdings limit will restrict your search to articles in journals subscribed to by the University of Vermont (UVM).

Additional limit options can be found by clicking on the More Limits button.   These include limits for age groups, journal subsets, and publication types such as clinical trials, randomized controlled trials, practice guidelines, meta analysis, or review articles.  Pull the scroll bar down to view the entire screen.

Limit in stepwise fashion rather than all at once so that you have the option of going back to a larger, less restricted set if necessary.  

Viewing and selecting citations

Click on the Display button for the set you wish to view.  The citations will be listed in reverse chronological order (most recent listed first.)  The citations will be displayed in the brief format, which includes citation, publication type, local holdings message, and unique identifier (UI).  The minimum information required to locate an article is listed in italics and consists of the journal title, volume, issue, page numbers, and date.

To view the abstract or the complete reference - which includes the subject headings and additional database fields, but not the full-text of the article - click on the appropriate hyperlink. The author name subject headings will be hyperlinked, enabling you to launch new searches instantly. 

All abstracts and subject headings will appear in English even though the article itself may be written in a non-English language. 

To check the UVM Libraries Online Catalog for available issues, click on the Library Holdings link, opening a new browser window.  If UVM has an electronic subscription to the journal, a URL will be provided which will direct you to the publisher's website.  Browse the archive of past issues for the desired article.  Click on Return to Session to resume your Ovid MEDLINEŽ search.

The Ovid Full Text button links to electronic journals that UVM subscribes to through Ovid.  To view a list of these journals, go to Dana Library's home page and click on Electronic Journal Packages under the Electronic Journals heading.

Check the boxes on the left margin to mark any records you wish to save for printing or e-mailing.  When you are finished browsing the set, click on Main Search Page.  A new set will have been created consisting of the records you selected. 

Printing, emailing, and saving results

Scroll down to the Results Manager located at the bottom of the page.  Indicate which citations you want and the desired fields (the default is Citation + Abstract).  Always check Include Search History so that you can repeat your search at a later date if necessary. 

To print the results, click on Print Preview, followed by your browser's print function.  To e-mail or save the citations, click on the appropriate button and follow the prompts. 

Getting the full-text of the article

Use the Local Holdings limit to restrict your search to journals subscribed to by UVM, either electronically or in print. 

To check the UVM Libraries Online Catalog for available issues, click on the Library Holdings link.  If UVM has an electronic subscription to the journal, a URL will be provided that will take you to the publisher's website.  Browse the archive of past issues for the particular article.

The Ovid Full Text button links to electronic journals that UVM subscribes to through Ovid.  To view a list of journals subscribed to through Ovid, go to Dana Library's home page, and click on Electronic Journal Packages under the Electronic Journals heading. 

For off-campus access to UVM electronic journals, refer to the Connect From Off Campus link on the Dana Library home page. 

Journals available in print are shelved alphabetically by title in the periodical section of Dana Library.  Journals dated pre-1985 are housed in the Library Research Annex, located on Catamount Drive next to UVM Police Services on the east side of East Avenue.  Consult the UVM Libraries Online Catalog for detailed information about specific journal titles. 

Unbound journal issues from the current year are shelved in the lounge area.

Author, title, or journal searches

To search for articles written by a specific author, click on the Author tab above the search box.  Enter the author's last name, a space, and the first letter of the first name.  Select all variations of the name, noting that an author may be listed with only a first initial or with both the first and middle initials. 

To search for an article for which you only know a word or phrase from its title, click on the Title tab, and enter the word or phrase in the search box.

To search for all articles in the MEDLINE database from a given journal, click on the Journal tab.  Enter the first word or two of the full journal title (do not use abbreviations.)  

Find similar articles and citing articles

Find Similar and Find Citing Articles permit you to expand a search without ever having to enter additional terms.  They are excellent tools for finding additional articles when your search is producing too few results or when you need to perform a highly comprehensive search.  Simply click on the appropriate link in the brief (default), abstract, or complete reference display. 

Find Citing Articles connects you to a list of more recent articles that cite the original article.  It is most useful for older articles, since it takes a number of years before an article will be cited by new publications.  By clicking on Complete Reference for a citing article, the entire bibliography of the citing article will be displayed, including the original article. 

Clinical Queries

This feature is found by clicking on the More Limits button. 

The Clinical Queries feature is intended for use by clinicians wishing to restrict their searches to clinically sound research studies.  There are nine broad categories of searches available: Therapy, Diagnosis, Prognosis, Etiology, Reviews, Clinical Prediction Guides, Qualitative Studies, Costs, and Economics.  Each of these search categories may in turn be designated as sensitive, specific, or optimized.  A sensitive search will bring up most relevant articles but some less relevant ones as well, a specific search will bring up most of the relevant articles but miss a few of them, and an optimized search will attempt to balance sensitivity with specificity. 

These filters are based on the work of R. Brian Haynes, MD, PhD et al. of the Health Information Research Unit at McMaster University.  A detailed explanation of these limits can be found at http://hiru.mcmaster.ca/hedges/.

Troubleshooting

Q.  What do I do if I get too many results? 

  • add another search term, using "AND" to make a smaller set
  • substitute a more specific term
  • remove the Explode feature
  • add the Focus feature
  • add one or more subheadings
  • place a limit on the final results (e.g., publication type, age group, publication year, etc.,)

Q.  What do I do if I get too few results?

  • remove a term if you combined more than one term with AND
  • search on related terms, using OR to make a larger set
  • substitute a more general term
  • add the Explode feature
  • remove the Focus feature
  • remove subheadings, and instead accept the default of All Subheadings
  • remove limits, broaden them, or apply them incrementally

For more help

If you would like more help with searching Ovid MEDLINEŽ or any of the other bibliographic databases, please call the Dana Medical Library Reference Desk at 656-2201, send an email to danaref@uvm.edu, or send an AOL Instant Message to our screen name "danaref". Or even (gasp!), come see us in person.  We also offer private tutorials and classes to individuals and small groups.  Call the reference desk for more information. 

Frances Delwiche, Reference Librarian, Dana Medical Library, University of Vermont, fdelwich@uvm.edu 01/18/06